The Tenth International Conference "Inverse Problems: Modelling and Simulation" (IPMS 2022) will be held during May 22-28, 2022 at the Congress Center of the Paradise Bay Hotel, Mellieha, Malta. The IPMS conference series is one of the main scientific meetings of the field which has been organized every two years since 2002, under the auspices of The Eurasian Association on Inverse Problems (EAIP). The Conference IPMS 2022 is the tenth (Jubilee) in the series. The objective of this meeting is to be multidisciplinary and international, bringing together scientists working on various topics of inverse problems in diverse areas. An important goal of the IPMS conferences is to encourage the participation of young researchers by offering them the opportunity to deliver invited talks and by partially supporting them. We look forward to welcoming you to Malta.